The Aging Cardiovascular System

Mitophagy: New Insight into the Cardiovascular Aging  

Aging and the Cardiovascular System

T he progressive aging of the population is a phenomenon of our era. Aging is characterized by a progressive organ dysfunction that complicates the maintenance of homeostasis. However, there is no universal definition of senility. Physiological changes occurring with aging do not appear at any definite time. The majority of definitions of aging are based on calendar age. The World Health Organi...

Physiology of Aging Invited Review: Aging and the cardiovascular system

Ferrari, Alberto U., Alberto Radaelli, and Marco Centola. Invited Review: Aging and the cardiovascular system. J Appl Physiol 95: 2591–2597, 2003; 10.1152/japplphysiol.00601.2003.—Aging is associated with complex and diversified changes of cardiovascular structure and function. The heart becomes slightly hypertrophic and hyporesponsive to sympathetic (but not parasympathetic) stimuli, so that t...

Aging-Related Changes of the Cardiovascular System

The cardiovascular system (CVS) is associated with many complex changes during aging both in structure and function, which leads to alterations in of the cardiovascular physiology that differ from pathological effects such as disease of the coronary arteries. The changes related to age seen in everyone but not necessarily at the same rate. The related change of the CVS with aging includes sligh...

Effects of Aging on the Cardiovascular System

Advanced age is a major risk factor for the development of cardiovascular disease. Why age increases the risk of cardiovascular disease is debatable. The increased risk might arise simply because there is more time to be exposed to risk factors such as hypertension, smoking, and dyslipidemia. In other words, the aging process itself has little impact on the cardiovascular system. However, an em...